CMM-Bio

New algorithmic ideas for the “de novo” assembly of human populations

Event Date: Dec 05, 2018 in CMM-Bio, Seminars

Abstract: Decoding the genome of the entire human population is currently regarded as a feasible task due to the accelerated development of sequencing technologies. Two major approaches have been proposed to decode the genomic sequence of human individuals namely resequencing and de novo assembly. Currently, resequencing is the dominant approach and consists in sequencing genomic fragments (reads) and compares them to the human reference sequence. Contrary to the resequencing idea, the de novo assembly approach compute overlaps among the sequenced reads and build the genome sequence without...